Antenatal allopurinol for reduction of birth asphyxia induced brain damage (ALLO-Trial); a randomized double blind placebo controlled multicenter study

BACKGROUND: Hypoxic-ischaemic encephalopathy is associated with development of cerebral palsy and cognitive disability later in life and is therefore one of the fundamental problems in perinatal medicine. The xanthine-oxidase inhibitor allopurinol reduces the formation of free radicals, thereby limi...

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Detalhes bibliográficos
Main Authors: Kaandorp, Joepe J, Benders, Manon JNL, Rademaker, Carin MA, Torrance, Helen L, Oudijk, Martijn A, de Haan, Timo R, Bloemenkamp, Kitty WM, Rijken, Monique, van Pampus, Maria G, Bos, Arie F, Porath, Martina M, Oetomo, Sidarto Bambang, Willekes, Christine, Gavilanes, AW Danilo, Wouters, Maurice GAJ, van Elburg, Ruurd M, Huisjes, Anjoke JM, Bakker, Saskia CMJER, van Meir, Claudia A, von Lindern, Jeannette, Boon, Janine, de Boer, Inge P, Rijnders, Robbert JP, Jacobs, Corrie JWFM, Uiterwaal, Cuno SPM, Mol, Ben Willem J, Visser, Gerard HA, van Bel, Frank, Derks, Jan B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Study protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834613/
https://ncbi.nlm.nih.gov/pubmed/20167117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2393-10-8
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