Vandetanib for the Treatment of Patients With Locally Advanced or Metastatic Hereditary Medullary Thyroid Cancer

PURPOSE: There is no effective therapy for patients with distant metastasis of medullary thyroid carcinoma (MTC). Activating mutations in the RET proto-oncogene cause hereditary MTC, which provides a strong therapeutic rationale for targeting RET kinase activity. This open-label, phase II study asse...

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Hlavní autoři: Wells, Samuel A., Gosnell, Jessica E., Gagel, Robert F., Moley, Jeffrey, Pfister, David, Sosa, Julie A., Skinner, Michael, Krebs, Annetta, Vasselli, James, Schlumberger, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2010
Témata:
Original Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834392/
https://ncbi.nlm.nih.gov/pubmed/20065189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.23.6604
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