Variation in the upstream region of P-Selectin (SELP) is a risk factor for SLE

Systemic lupus erythematosus (SLE) is a complex autoimmune disease. Genome-wide linkage studies implicated a region containing the adhesion molecule P-Selectin. This family-based study revealed two regions of association within P-Selectin. The strongest signal, from a 21.4-kb risk haplotype, stretch...

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Hlavní autoři: Morris, D L, Graham, R R, Erwig, L-P, Gaffney, P M, Moser, K L, Behrens, T W, Vyse, T J, Graham, D S Cunninghame
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834331/
https://ncbi.nlm.nih.gov/pubmed/19404301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2009.17
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