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A Model of Best Vitelliform Macular Dystrophy in Rats

PURPOSE: The VMD2 gene, mutated in Best macular dystrophy (BMD) encodes bestrophin, a 68-kDa basolateral plasma membrane protein expressed in retinal pigment epithelial (RPE) cells. BMD is characterized by a depressed light peak (LP) in the electro-oculogram. Bestrophin is thought to be the Cl chann...

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Autors principals: Marmorstein, Alan D., Stanton, J. Brett, Yocom, John, Bakall, Benjamin, Schiavone, Marc T., Wadelius, Claes, Marmorstein, Lihua Y., Peachey, Neal S.
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834278/
https://ncbi.nlm.nih.gov/pubmed/15452084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.04-0307
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