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Age-related Changes in Mitochondrial Respiration and Oxidative Damage in the Cerebral Cortex of the Fischer 344 Rat

This study probed possible age-related changes in mitochondrial bioenergetics in naïve Fischer 344 rats. Synaptic and extrasynaptic mitochondria were isolated from the cortex of one hemisphere of young (3–5 mos), middle (12–14 mos), or aged (22–24 mos) rats. Respiration parameters were obtained usin...

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Detalhes bibliográficos
Main Authors: Gilmer, Lesley K., Ansari, Mubeen A., Roberts, Kelly N., Scheff, Stephen W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834189/
https://ncbi.nlm.nih.gov/pubmed/20080122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2009.12.011
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