ENGINEERED MODULAR RECOMBINANT TRANSPORTERS: APPLICATION OF NEW PLATFORM FOR TARGETED RADIOTHERAPEUTIC AGENTS TO α-PARTICLE EMITTING (211)At

PURPOSE: To generate and evaluate a modular recombinant transporter (MRT) for targeting (211)At to cancer cells overexpressing the epidermal growth factor receptor (EGFR). METHODS AND MATERIALS: The MRT was produced with four functional modules: (1) human epidermal growth factor as the internalizabl...

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Main Authors: Rosenkranz, Andrey A., Vaidyanathan, Ganesan, Pozzi, Oscar R., Lunin, Vladimir G., Zalutsky, Michael R., Sobolev, Alexander S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834178/
https://ncbi.nlm.nih.gov/pubmed/18722270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2008.05.055
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