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Fluence Rate-Dependent Intratumor Heterogeneity in Physiologic and Cytotoxic Responses to Photofrin Photodynamic Therapy

Photodynamic therapy (PDT) can lead to the creation of heterogeneous, response-limiting hypoxia during illumination, which may be controlled in part through illumination fluence rate. In the present report we consider 1) regional differences in hypoxia, vascular response, and cell kill as a function...

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Autors principals: Busch, Theresa M., Xing, Xiaoman, Yu, Guoqiang, Yodh, Arjun, Wileyto, E. Paul, Wang, Hsing-Wen, Durduran, Turgut, Zhu, Timothy C., Wang, Ken Kang-Hsin
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834171/
https://ncbi.nlm.nih.gov/pubmed/20024165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b9pp00004f
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