Intra-articular steroid treatment reduces synovial HMGB1 but not IL-1 expression in chronic arthritis

Eitemau Tebyg

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• Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients – a prospective clinical study
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• Patterns of gene expression in rheumatoid arthritis synovial tissue: inter-patient variability greater then intra-patient variability in a small study
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  Cyhoeddwyd: (2005)
• HMGB1, a new proinflammatory molecule of interest in polymyositis and dermatomyositis patients
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  Cyhoeddwyd: (2003)
• Synovial expression of IL-15 in rheumatoid arthritis is not influenced by blockade of tumour necrosis factor
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  Cyhoeddwyd: (2006)