DNA Methylome of Familial Breast Cancer Identifies Distinct Profiles Defined by Mutation Status

It is now understood that epigenetic alterations occur frequently in sporadic breast carcinogenesis, but little is known about the epigenetic alterations associated with familial breast tumors. We performed genome-wide DNA-methylation profiling on familial breast cancers (n = 33) to identify pattern...

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Hlavní autoři: Flanagan, James M., Cocciardi, Sibylle, Waddell, Nic, Johnstone, Cameron N., Marsh, Anna, Henderson, Stephen, Simpson, Peter, da Silva, Leonard, Khanna, Kumkum, Lakhani, Sunil, Boshoff, Chris, Chenevix-Trench, Georgia
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833389/
https://ncbi.nlm.nih.gov/pubmed/20206335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.02.008
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