Amplification of chromosomal segment 4q12 in non-small cell lung cancer

In cancer, proto-oncogenes are often altered by genomic amplification. Here we report recurrent focal amplifications of chromosomal segment 4q12 overlapping the proto-oncogenes PDGFRA and KIT in non-small cell lung cancer (NSCLC). Single nucleotide polymorphism (SNP) array and fluorescent in situ hy...

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Hlavní autoři: Ramos, Alex H., Dutt, Amit, Mermel, Craig, Perner, Sven, Cho, Jeonghee, Lafargue, Christopher J., Johnson, Laura A., Stiedl, Ann-Cathrin, Tanaka, Kumiko E., Bass, Adam J., Barretina, Jordi, Weir, Barbara A., Beroukhim, Rameen, Thomas, Roman K., Minna, John D., Chirieac, Lucian R., Lindeman, Neal I., Giordano, Thomas, Beer, David G., Wagner, Patrick, Wistuba, Ignacio I., Rubin, Mark A., Meyerson, Matthew
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833355/
https://ncbi.nlm.nih.gov/pubmed/19755855
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