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Release of Pituitary Growth Hormone by Prostaglandins and Dibutyryl Adenosine Cyclic 3′:5′-Monophosphate in the Absence of Protein Synthesis

Effects of prostaglandins on the incorporation of [4,5-(3)H]leucine into growth hormone and its subsequent release into the incubation medium were studied. Incubation of rat anterior pituitary glands with 10(-6) M prostaglandin PGE(1) in tissue culture medium 199 for 7 hr caused a 40-300% increase i...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: MacLeod, Robert M., Lehmeyer, Joyee E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1970
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283333/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4320973/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.3.1172
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