Reversible Inhibitors of Monoamine Oxidase-A (RIMAs): Robust, Reversible Inhibition of Human Brain MAO-A by CX157

Reversible inhibitors of monoamine oxidase-A (RIMA) inhibit the breakdown of three major neurotransmitters, serotonin, norepinephrine and dopamine, offering a multi-neurotransmitter strategy for the treatment of depression. CX157 (3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin-10,10-dioxide) is a RI...

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Detalhes bibliográficos
Main Authors: Fowler, Joanna S, Logan, Jean, Azzaro, Albert J, Fielding, Robert M, Zhu, Wei, Poshusta, Amy K, Burch, Daniel, Brand, Barry, Free, James, Asgharnejad, Mahnaz, Wang, Gene-Jack, Telang, Frank, Hubbard, Barbara, Jayne, Millard, King, Payton, Carter, Pauline, Carter, Scott, Xu, Youwen, Shea, Colleen, Muench, Lisa, Alexoff, David, Shumay, Elena, Schueller, Michael, Warner, Donald, Apelskog-Torres, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833271/
https://ncbi.nlm.nih.gov/pubmed/19890267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.167
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