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COMPARISON OF ONCE-DAILY VERSUS TWICE-DAILY COMBINATION ANTIRETROVIRAL THERAPY IN TREATMENT-NAÏVE PATIENTS: RESULTS OF AIDS CLINICAL TRIALS GROUP (ACTG) A5073, A 48-WEEK RANDOMIZED CONTROLLED TRIAL
BACKGROUND: Dosing frequency is an important determinant of regimen effectiveness. METHODS: To compare efficacy of once-daily (QD) versus twice-daily (BID) antiretroviral therapy, we randomized HIV-1 positive, treatment-naïve, patients to lopinavir/ritonavir (LPV/r) 400/100 mg BID (n=160) or LPV/r 8...
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Main Authors: | , , , , , , , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2010
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2833234/ https://ncbi.nlm.nih.gov/pubmed/20192725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/651118 |
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