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Mutant Mouse Models: Genotype-Phenotype Relationships to Negative Symptoms in Schizophrenia

Negative symptoms encompass diminution in emotional expression and motivation, some of which relate to human attributes that may not be accessible readily in animals. Additionally, their refractoriness to treatment precludes therapeutic validation of putative models. This review considers critically...

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Autores principales: O'Tuathaigh, Colm M. P., Kirby, Brian P., Moran, Paula M., Waddington, John L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833123/
https://ncbi.nlm.nih.gov/pubmed/19934211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbp125
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