Mutant Mouse Models: Genotype-Phenotype Relationships to Negative Symptoms in Schizophrenia

Negative symptoms encompass diminution in emotional expression and motivation, some of which relate to human attributes that may not be accessible readily in animals. Additionally, their refractoriness to treatment precludes therapeutic validation of putative models. This review considers critically...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: O'Tuathaigh, Colm M. P., Kirby, Brian P., Moran, Paula M., Waddington, John L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2010
Pynciau:
Theme: Mutant Mouse Models: Phenotypic Relationships to Domains of Psychopathology and Pathobiology in Schizophrenia Guest Editors: John L. Waddington and Colm M. P. O'Tuathaigh
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833123/
https://ncbi.nlm.nih.gov/pubmed/19934211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbp125
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