Mutant Mouse Models: Genotype-Phenotype Relationships to Negative Symptoms in Schizophrenia

Negative symptoms encompass diminution in emotional expression and motivation, some of which relate to human attributes that may not be accessible readily in animals. Additionally, their refractoriness to treatment precludes therapeutic validation of putative models. This review considers critically...

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Detalhes bibliográficos
Main Authors: O'Tuathaigh, Colm M. P., Kirby, Brian P., Moran, Paula M., Waddington, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Theme: Mutant Mouse Models: Phenotypic Relationships to Domains of Psychopathology and Pathobiology in Schizophrenia Guest Editors: John L. Waddington and Colm M. P. O'Tuathaigh
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833123/
https://ncbi.nlm.nih.gov/pubmed/19934211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbp125
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