Unimpaired terminal erythroid differentiation and preserved enucleation capacity in myelodysplastic 5q(del) clones: a single cell study

BACKGROUND: Anemia is a characteristic of myelodysplastic syndromes, such as the rare 5q- syndrome, but its mechanism remains unclear. In particular, data are lacking on the terminal phase of differentiation of erythroid cells (enucleation) in myelodysplastic syndromes. DESIGN AND METHODS: We used a...

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Main Authors: Garderet, Laurent, Kobari, Ladan, Mazurier, Christelle, De Witte, Caroline, Giarratana, Marie-Catherine, Pérot, Christine, Gorin, Norbert Claude, Lapillonne, Hélène, Douay, Luc
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2010
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833069/
https://ncbi.nlm.nih.gov/pubmed/19815832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.012773
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