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LRRK2 is a component of granular alpha-synuclein pathology in the brainstem of Parkinson's disease

Classical Parkinson's disease (PD) is characterized by the appearance of Lewy bodies (LBs) in affected brain regions, showing mostly compact alpha-synuclein deposition, in contrast with punctate or granular deposition, hypothesized to represent early stages of aggregation. Leucine-rich repeat k...

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Autores principales: Alegre-Abarrategui, Javier, Ansorge, Olaf, Esiri, Margaret, Wade-Martins, Richard
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833010/
https://ncbi.nlm.nih.gov/pubmed/17971075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2990.2007.00888.x
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