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Interallelic Complementation in Hybrid Cells Derived from Human Diploid Strains Deficient in Galactose-1-Phosphate Uridyl Transferase Activity

Galactose-1-phosphate uridyl transferase activity has been demonstrated in hybrid cells formed from the fusion of human diploid fibroblasts obtained from different patients with galactosemia. The enzyme produced by the hybrid cells was similar to the normal enzyme in regard to K(m), pH optimum, and...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Nadler, Henry L., Chacko, Claramma M., Rachmeler, Martin
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1970
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283301/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5289034/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.2.976
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