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Ultraviolet Radiation Stress Triggers the Down-regulation of Essential Replication Factor Mcm10
We report that upon UV radiation insult, mammalian cells specifically down-regulate Mcm10, a protein essential for the initiation and elongation phases of DNA replication. The levels of a majority of replication factors remain unaffected under this condition, implying that Mcm10 is a key node in the...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832985/ https://ncbi.nlm.nih.gov/pubmed/20064936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.041129 |
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