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NF45 and NF90 Regulate HS4-dependent Interleukin-13 Transcription in T Cells

Expression of the cytokine interleukin-13 (IL13) is critical for Th2 immune responses and Th2-mediated allergic diseases. Activation of human IL13 expression involves chromatin remodeling and formation of multiple DNase I-hypersensitive sites throughout the locus. Among these, HS4 is detected in the...

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Main Authors: Kiesler, Patricia, Haynes, Paul A., Shi, Lingfang, Kao, Peter N., Wysocki, Vicki H., Vercelli, Donata
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832977/
https://ncbi.nlm.nih.gov/pubmed/20051514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.041004
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