Meta-analyses of genome-wide association studies identify multiple novel loci associated with pulmonary function

Measurements of lung function by spirometry are heritable traits that reflect respiratory health and predict morbidity and mortality. We meta-analyzed genome-wide association studies for two clinically important measures, forced expiratory volume in the first second (FEV(1)) and its ratio to forced...

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Detalhes bibliográficos
Main Authors: Hancock, Dana B., Eijgelsheim, Mark, Wilk, Jemma B., Gharib, Sina A., Loehr, Laura R., Marciante, Kristin D., Franceschini, Nora, van Durme, Yannick M.T.A., Chen, Ting-hsu, Barr, R. Graham, Schabath, Matthew B., Couper, David J., Brusselle, Guy G., Psaty, Bruce M., van Duijn, Cornelia M., Rotter, Jerome I., Uitterlinden, André G., Hofman, Albert, Punjabi, Naresh M., Rivadeneira, Fernando, Morrison, Alanna C., Enright, Paul L., North, Kari E., Heckbert, Susan R., Lumley, Thomas, Stricker, Bruno H.Ch., O’Connor, George T., London, Stephanie J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832852/
https://ncbi.nlm.nih.gov/pubmed/20010835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.500
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