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Characterization of new metabolites from in vivo biotransformation of 2-amino-3-methylimidazo[4,5-f]quinoline in mouse by mass spectrometry

In studying the metabolic pathways underlying the mechanism of carcinogenesis of the heterocyclic amine of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), we recently found a new metabolite, which gave a [M + H](+) ion of m/z 217 when subjected to ESI in positive-ion mode. Following ip injection of th...

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Detalhes bibliográficos
Main Authors: Hsu, Fong-Fu, Lakshmi, Vijaya M., Zenser, Terry V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832803/
https://ncbi.nlm.nih.gov/pubmed/19629964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.1620
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