Direct Restriction of Virus Release and Incorporation of the Interferon-Induced Protein BST-2 into HIV-1 Particles

Investigation of the Vpu protein of HIV-1 recently uncovered a novel aspect of the mammalian innate response to enveloped viruses: retention of progeny virions on the surface of infected cells by the interferon-induced, transmembrane and GPI-anchored protein BST-2 (CD317; tetherin). BST-2 inhibits d...

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Autori principali: Fitzpatrick, Kathleen, Skasko, Mark, Deerinck, Thomas J., Crum, John, Ellisman, Mark H., Guatelli, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832767/
https://ncbi.nlm.nih.gov/pubmed/20221443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000701
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