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Structural Plasticity of Eph Receptor A4 Facilitates Cross-Class Ephrin Signaling
The EphA4 tyrosine kinase cell surface receptor regulates an array of physiological processes and is the only currently known class A Eph receptor that binds both A and B class ephrins with high affinity. We have solved the crystal structure of the EphA4 ligand binding domain alone and in complex wi...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cell Press
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832735/ https://ncbi.nlm.nih.gov/pubmed/19836338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.07.018 |
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