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Inhibition of SIRT1 deacetylase suppresses estrogen receptor signaling
Estrogen receptor α (ERα) mediates estrogen-dependent gene transcription, which plays a critical role in mammary gland development, reproduction and homeostasis. Histone acetyltransferases and class I and class II histone deacetylases (HDACs) cause posttranscriptional modification of histone protein...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832546/ https://ncbi.nlm.nih.gov/pubmed/19995796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp308 |
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