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Conformational flexibility of the ATPase SecA enables peptide interaction and translocation

The SecA ATPase forms a functional complex with the protein conducting SecY channel to translocate polypeptides across the bacterial cell membrane. SecA recognizes the translocation substrate and catalyzes its unidirectional movement through the SecY channel. The recent crystal structure of the Ther...

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Bibliographic Details
Main Authors: Zimmer, Jochen, Rapoport, Tom A.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832196/
https://ncbi.nlm.nih.gov/pubmed/19850053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.10.024
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