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Left-Sided Cardiac Valvulitis in Tristetraprolin-Deficient Mice: The Role of Tumor Necrosis Factor α
Inflammation may play a role in the etiology of both degenerative and rheumatic cardiac valve diseases. We report here that mice deficient in tristetraprolin (TTP), a protein with known anti-inflammatory functions, develop severe left-sided cardiac valvulitis. TTP is an mRNA binding protein that inh...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Investigative Pathology
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832167/ https://ncbi.nlm.nih.gov/pubmed/20093488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090498 |
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