Dermal Collagen and Lipid Deposition Correlate with Tissue Swelling and Hydraulic Conductivity in Murine Primary Lymphedema

Primary lymphedema is a congenital pathology of dysfunctional lymphatic drainage characterized by swelling of the limbs, thickening of the dermis, and fluid and lipid accumulation in the underlying tissue. Two mouse models of primary lymphedema, the Chy mouse and the K14-VEGFR-3-Ig mouse, both lack...

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Bibliografiske detaljer
Main Authors: Rutkowski, Joseph M., Markhus, Carl Erik, Gyenge, Christina C., Alitalo, Kari, Wiig, Helge, Swartz, Melody A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2010
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832135/
https://ncbi.nlm.nih.gov/pubmed/20110415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090733
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