Dermal Collagen and Lipid Deposition Correlate with Tissue Swelling and Hydraulic Conductivity in Murine Primary Lymphedema

Primary lymphedema is a congenital pathology of dysfunctional lymphatic drainage characterized by swelling of the limbs, thickening of the dermis, and fluid and lipid accumulation in the underlying tissue. Two mouse models of primary lymphedema, the Chy mouse and the K14-VEGFR-3-Ig mouse, both lack...

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Главные авторы: Rutkowski, Joseph M., Markhus, Carl Erik, Gyenge, Christina C., Alitalo, Kari, Wiig, Helge, Swartz, Melody A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2010
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Regular Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832135/
https://ncbi.nlm.nih.gov/pubmed/20110415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090733
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