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The chemotherapy agent, thioTEPA, yields long-term impairment of hippocampal cell proliferation and memory deficits but not depression-related behaviors in mice

ThioTEPA is a chemotherapeutic agent used in the treatment of cancers, and more recently has been proposed as a component of high-dose therapy for young patients with recurrent malignant brain tumors. We previously demonstrated a significant dose-dependent reduction of cell proliferation in the dent...

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Bibliografske podrobnosti
Main Authors: Mondie, Christopher M., Vandergrift, Kelley A., Wilson, Courtney L., Gulinello, Maria E., Weber, E. Todd
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832075/
https://ncbi.nlm.nih.gov/pubmed/20096731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2010.01.016
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