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Atomic resolution protein structure determination by three-dimensional transferred echo double resonance solid-state nuclear magnetic resonance spectroscopy

We show that quantitative internuclear (15)N–(13)C distances can be obtained in sufficient quantity to determine a complete, high-resolution structure of a moderately sized protein by magic-angle spinning solid-state NMR spectroscopy. The three-dimensional ZF-TEDOR pulse sequence is employed in comb...

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Bibliografiske detaljer
Main Authors: Nieuwkoop, Andrew J., Wylie, Benjamin J., Franks, W. Trent, Shah, Gautam J., Rienstra, Chad M.
Format: Artigo
Sprog:Inglês
Udgivet: American Institute of Physics 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832044/
https://ncbi.nlm.nih.gov/pubmed/19739873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3211103
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