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Oseltamivir Carboxylate, the Active Metabolite of Oseltamivir Phosphate (Tamiflu), Detected in Sewage Discharge and River Water in Japan

BACKGROUND: Oseltamivir phosphate (OP; Tamiflu) is a prodrug of the anti-influenza neuraminidase inhibitor oseltamivir carboxylate (OC) and has been developed for the treatment and prevention of both A and B strains of influenza. The recent increase in OP resistance in influenza A virus (H1N1; commo...

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Detalhes bibliográficos
Main Authors: Ghosh, Gopal C., Nakada, Norihide, Yamashita, Naoyuki, Tanaka, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831951/
https://ncbi.nlm.nih.gov/pubmed/20056566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.0900930
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