An Approach to Conformational Analysis of Peptides and Proteins in Solution Based on a Combination of Nuclear Magnetic Resonance Spectroscopy and Conformational Energy Calculations
Simple criteria, based on the combined use of nmr spectral parameters and potential energy maps, are proposed for the conformational analysis of polypeptides and proteins. Experimentally determined coupling constants (3)J(NC) for the N-C(α) bond are consistent with the Karplus-Bystrov relationship....
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1970
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283194/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5272315/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.1.239 |
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