Neonatal Organophosphorus Pesticide Exposure Alters the Developmental Trajectory of Cell-Signaling Cascades Controlling Metabolism: Differential Effects of Diazinon and Parathion

BACKGROUND: Organophosphorus pesticides (OPs) are developmental neurotoxicants but also produce lasting effects on metabolism. OBJECTIVES/METHODS: We administered diazinon (DZN) or parathion (PRT) to rats on postnatal days 1–4 at doses straddling the threshold for systemic signs of exposure and asse...

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Autores principales: Adigun, Abayomi A., Wrench, Nicola, Seidler, Frederic J., Slotkin, Theodore A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Institute of Environmental Health Sciences 2010
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831919/
https://ncbi.nlm.nih.gov/pubmed/20123610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.0901237
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