ZONAB Promotes Proliferation and Represses Differentiation of Proximal Tubule Epithelial Cells

Epithelial polarization modulates gene expression. The transcription factor zonula occludens 1 (ZO-1)–associated nucleic acid binding protein (ZONAB) can shuttle between tight junctions and nuclei, promoting cell proliferation and expression of cyclin D1 and proliferating cell nuclear antigen (PCNA)...

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Autori principali: Lima, Wânia R., Parreira, Kleber S., Devuyst, Olivier, Caplanusi, Adrian, N′Kuli, Francisca, Marien, Benoit, Van Der Smissen, Patrick, Alves, Pedro M.S., Verroust, Pierre, Christensen, Erik I., Terzi, Fabiola, Matter, Karl, Balda, Maria S., Pierreux, Christophe E., Courtoy, Pierre J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2010
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831853/
https://ncbi.nlm.nih.gov/pubmed/20133480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009070698
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