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An effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq data

BACKGROUND: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of protein-DNA interactions in vivo in the genome. However, to maximize the effectiveness of data analysis of such sequences req...

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Bibliografiske detaljer
Main Authors: Wang, Congmao, Xu, Jie, Zhang, Dasheng, Wilson, Zoe A, Zhang, Dabing
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831849/
https://ncbi.nlm.nih.gov/pubmed/20144209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-81
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