Degradation of a Pneumococcal Type-Specific Polysaccharide with Exposure of Group-Specificity

Pyruvic acid is an immunological determinant of the quite rigorously type-specific capsular polysaccharide of pneumococcal type IV (S IV). Removal of pyruvic acid by mild hydrolysis converts the capsular polysaccharide of type IV into an analog of the pneumococcal group-specific C-substance. Depyruv...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Higginbotham, John D., Heidelberger, Michael, Gotschlich, Emil C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1970
Soggetti:	Biological Sciences: Immunology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283179/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4394061/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.67.1.138
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