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Synthesis and Secretion of γ-Globulin by Lymph Node Cells, VIII. Order of Synthesis of the Interchain Disulfide Linkages of Immunoglobulins

Murine myeloma cells (ADJ-PC-5), incubated in vitro with (3)H-leucine, secrete (3)H-immunoglobulin G as a single molecular species as judged by the migration characteristics of the labeled product on sodium dodecyl sulfateacrylamide gel electrophoresis. However, the fact that some of the interchain...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Sutherland, Earl W., Zimmerman, Daniel H., Kern, Milton
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1970
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283148/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5269257/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.66.3.987
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