Translational activation of rpoS mRNA by the non-coding RNA DsrA and Hfq does not require ribosome binding

At low temperature, translational activation of rpoS mRNA, encoding the stationary phase sigma-factor, σ(S), involves the small regulatory RNA (sRNA) DsrA and the RNA chaperone Hfq. The Hfq-mediated DsrA-rpoS interaction relieves an intramolecular secondary structure that impedes ribosome access to...

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Bibliographic Details
Main Authors: Večerek, Branislav, Beich-Frandsen, Mads, Resch, Armin, Bläsi, Udo
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831331/
https://ncbi.nlm.nih.gov/pubmed/19969548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1125
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