Vascular Endothelial Growth Factor (VEGF)-induced Up-regulation of CCN1 in Osteoblasts Mediates Proangiogenic Activities in Endothelial Cells and Promotes Fracture Healing

Angiogenesis is indispensable during fracture repair, and vascular endothelial growth factor (VEGF) is critical in this process. CCN1 (CYR61) is an extracellular matrix signaling molecule that has been implicated in neovascularization through its interactions with several endothelial integrin recept...

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Main Authors: Athanasopoulos, Athanasios N., Schneider, Darius, Keiper, Tanja, Alt, Volker, Pendurthi, Usha R., Liegibel, Ute M., Sommer, Ulrike, Nawroth, Peter P., Kasperk, Christian, Chavakis, Triantafyllos
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831223/
https://ncbi.nlm.nih.gov/pubmed/17626014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705200200
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