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Activation of the Ubiquitin Proteasome System in Doxorubicin Cardiomyopathy

Doxorubicin (Dox) is a very potent anti-cancer agent but its usage is limited by its dose-dependent irreversible cardiotoxicity. Despite intensive research efforts, the mechanism of Dox cardiotoxicity remains to be poorly understood and consequently the means available for clinicians to prevent or e...

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Detalhes bibliográficos
Main Authors: Ranek, Mark J., Wang, Xuejun
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831222/
https://ncbi.nlm.nih.gov/pubmed/19895749
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