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Testing the theory of immune selection in cancers that break the rules of transplantation

Modification of cancer cells likely to reduce their immunogenicity, including loss or down-regulation of MHC molecules, is now well documented and has become the main support for the concept of immune surveillance. The evidence that these modifications, in fact, result from selection by the immune s...

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Autori principali: Fassati, Ariberto, Mitchison, N. Avrion
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831185/
https://ncbi.nlm.nih.gov/pubmed/20033157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-009-0809-1
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