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The Rap1 Guanine Nucleotide Exchange Factor C3G Is Required for Preservation of Larval Muscle Integrity in Drosophila melanogaster

C3G is a guanine nucleotide exchange factor (GEF) and modulator of small G-protein activity, which primarily acts on members of the Rap GTPase subfamily. Via promotion of the active GTP bound conformation of target GTPases, C3G has been implicated in the regulation of multiple cellular and developme...

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Detalhes bibliográficos
Main Authors: Shirinian, Margret, Grabbe, Caroline, Popovic, Milica, Varshney, Gaurav, Hugosson, Fredrik, Bos, Hans, Rehmann, Holger, Palmer, Ruth H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831063/
https://ncbi.nlm.nih.gov/pubmed/20209136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009403
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