Role of STAT3 in In Vitro Transformation Triggered by TRK Oncogenes

TRK oncoproteins are chimeric versions of the NTRK1/NGF receptor and display constitutive tyrosine kinase activity leading to transformation of NIH3T3 cells and neuronal differentiation of PC12 cells. Signal Transducer and Activator of Transcription (STAT) 3 is activated in response to cytokines and...

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Bibliografiske detaljer
Main Authors: Miranda, Claudia, Fumagalli, Tiziana, Anania, Maria Chiara, Vizioli, Maria Grazia, Pagliardini, Sonia, Pierotti, Marco A., Greco, Angela
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831059/
https://ncbi.nlm.nih.gov/pubmed/20209132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009446
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