The Two Stem Cell MicroRNA Gene Clusters C19MC and miR-371-3 Are Activated by Specific Chromosomal Rearrangements in a Subgroup of Thyroid Adenomas

Thyroid adenomas are common benign human tumors with a high prevalence of about 5% of the adult population even in iodine sufficient areas. Rearrangements of chromosomal band 19q13.4 represent a frequent clonal cytogenetic deviation in these tumors making them the most frequent non-random chromosoma...

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Main Authors: Rippe, Volkhard, Dittberner, Lea, Lorenz, Verena N., Drieschner, Norbert, Nimzyk, Rolf, Sendt, Wolfgang, Junker, Klaus, Belge, Gazanfer, Bullerdiek, Jörn
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831057/
https://ncbi.nlm.nih.gov/pubmed/20209130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009485
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