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KIT AS A THERAPEUTIC TARGET IN MELANOMA
Recently, genetic alterations activating the receptor tyrosine kinase KIT have been demonstrated in some types of melanoma. KIT mutations can be successfully targeted by approved drugs in other cancers. Emerging evidence suggests that melanomas with KIT activation may also respond to KIT inhibitors...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2831053/ https://ncbi.nlm.nih.gov/pubmed/19847190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2009.334 |
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