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A tree-based method for the rapid screening of chemical fingerprints

BACKGROUND: The fingerprint of a molecule is a bitstring based on its structure, constructed such that structurally similar molecules will have similar fingerprints. Molecular fingerprints can be used in an initial phase of drug development for identifying novel drug candidates by screening large da...

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Detalhes bibliográficos
Main Authors: Kristensen, Thomas G, Nielsen, Jesper, Pedersen, Christian NS
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830925/
https://ncbi.nlm.nih.gov/pubmed/20047665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-5-9
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