Qβ-Replicase and E. coli Transcriptase: Requirements for Substrate Selection as Revealed by a Study of Base Analogs

Base selection by the Qβ-replicase and E. coli transcriptase has been studied using substrate analogs. Six analogs with normal hydrogen-bonding sites were polymerized by both enzymes. Three analogs containing ring substitutions which affect the conformation at the glycosyl bond would not substitute...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Kapuler, A. M., Spiegelman, S.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1970
Schlagworte:	Biological Sciences: Biochemistry
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283078/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4915889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.66.2.539
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