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CCR6 ligands inhibit HIV by inducing APOBEC3G

We have identified a postentry CCR6-dependent mechanism of inhibition of HIV occurring at an early stage of infection mediated by the induction of the host restriction factor apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G). We observed induction of APOBEC3G expression o...

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Detalhes bibliográficos
Main Authors: Lafferty, Mark K., Sun, Lingling, DeMasi, Leon, Lu, Wuyuan, Garzino-Demo, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830761/
https://ncbi.nlm.nih.gov/pubmed/20023216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-06-226423
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