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Coding and Conformational Properties of Oligonucleotides Modified with the Carcinogen N-2-Acetylaminofluorene

The present studies were undertaken to determine the mechanism by which attachment of the carcinogen N-2-acetylaminofluorene to guanosine residues in nucleic acids distors their structure and function. Oligonucleotides were modified with N-acetoxy-2-acetylaminofluorene, repurified, and their base co...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Grunberger, Dezider, Nelson, James H., Cantor, Charles R., Weinstein, I. Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283071/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5271176/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.66.2.488
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