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Cyclic AMP Receptor Protein of E. coli: Its Role in the Synthesis of Inducible Enzymes

A cyclic AMP binding protein has been purified over 100-fold from E. coli extracts. Protein purified from wild-type strains binds cyclic AMP with an apparent dissociation constant of 1-2 × 10(-6) M. Two mutant strains that are unresponsive to exogenous cyclic AMP have altered binding activity; the p...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Emmer, Michael, deCrombrugghe, Benoit, Pastan, Ira, Perlman, Robert
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1970
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283070/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4317918/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.66.2.480
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